Cellular and Molecular Mechanisms Underpinning Macrophage Activation during Remyelination
نویسندگان
چکیده
منابع مشابه
Cellular and Molecular Mechanisms Underpinning Macrophage Activation during Remyelination
Remyelination is an example of central nervous system (CNS) regeneration, whereby myelin is restored around demyelinated axons, re-establishing saltatory conduction and trophic/metabolic support. In progressive multiple sclerosis, remyelination is limited or fails altogether which is considered to contribute to axonal damage/loss and consequent disability. Macrophages have critical roles in bot...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2016
ISSN: 2296-634X
DOI: 10.3389/fcell.2016.00060